这个基因陷阱被插入在exon 1的上游,导致转录产物包含基因陷阱与exon 2融合的序列。通过 Western blot 分析,确认了蛋白质表达减少了75%。这个等位基因是部分功能缺失的(来源:J:175913)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Gene trapped
基因捕获载体的插入
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1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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