这个基因陷阱被插入在exon 1的上游,导致转录产物包含基因陷阱与exon 2融合的序列。通过 Western blot 分析,确认了蛋白质表达减少了75%。这个等位基因是部分功能缺失的(来源:J:175913)。
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The gene trap inserted upstream of exon 1 and resulted in a transcript containing the gene trap fused to exon 2. A 75% reduction in protein expression was confirmed by western blot analysis. This allele is hypomorphic. (J:175913)