Log In|Sign Up
中文
G2019S-LRRK2转基因是通过最小的CMV增强子和人类血小板衍生生长因子B亚基(PDGFB)启动子/增强子元件设计的，这些元件驱动表达全长的人类leucine-rich repeat kinase 2（LRRK2）基因。对LRRK2基因位点进行了靶向突变，以包含与常染色体显性、晚发性帕金森病相关的G2019S突变。构建了Line 340（来源：J:171645）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
