Esr1^tm1.1Ohl

Mice lack the sequence in exon 8 that encodes the AF-2 core (amino acids 543 to 549; LLLEMLD). A floxed neo cassette used for selection was removed by cre-mediated recombination. The expression of a slightly smaller protein was confirmed by western blot analysis on uterus extracts. (J:171276, J:175619, J:206373)