设计了一种靶向载体,其在前串联一个loxP位点,接着是核前体膜相关因子样(Narfl或Iop1)基因的exon 1下游的frt标记的诺卡因抗性(neo)基因元件,然后是一个在Narfl或Iop1基因exon 1下游的第二个loxP位点。通过Flp介导的重组,去除了neo基因元件。(来源:J:170523)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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