一段2.2千碱基的片段,包括1号外显子和部分1号内含子,通过同源重组被IRES betageo cassette替换。新选择标记被通过与携带精子-Cre的杂合鼠杂交去除。(来源:J:169656, J:184380)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count