将人类带有三核苷酸重复,导致79个谷氨酰胺延伸的HA标签的cDNA驱动小鼠神经元表达。这种谷氨酰胺序列的扩增与人类的脊髓小脑性共济失调3(SCA3)相关。产生了两条包含超过5个转录本的转基因品系。当未指明具体线号或合并线条时,用 pound 符号 (#) 表示。来源:(J:138381)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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插入
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1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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