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中文
设计了一个靶向载体，包含在5号外显子上游的loxP位点，随后是诺卡因抗性（neo）基因座，接着是一个单独的loxP位点位于5号外显子下游。通过Cre介导的重组，去除了5号外显子和neo基因座。这个预测会导致蛋白质功能丧失。通过酶学实验确认了血浆中羧基酯酶活性的缺失。（来源：J:168821）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
