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在exon 9的第1130-1132位，通过删除TTC三个碱基，产生了一个变异。这导致了第377位氨基酸残基的苯丙氨酸缺失。同时，一个在intron 8的5'端，距离TTC缺失608bp的位置插入了可剔除的PGK neomycin筛选载体。为了去除这个筛选元件，创始人小鼠与表达Cre的 mice进行了杂交。(来源：J:168526)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
