Exon 2两侧由两个loxP位点标记,随后在第一个loxP位点后,插入了一个由FRT序列包裹的PGK-Neo cassette,它位于exon 2的5'端内含子1中。通过FLPe介导的重组,移除了PGK-Neo的选择序列。(来源:J:168065)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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