Il3编码区域从Csf2起始,替换为相应的人类序列。人类的Il3仍由小鼠启动子调控,而Csf2的表达则由人类启动子控制。通过Cre介导的重组,选择性载体被去除。(来源:J:168302)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
BALB/cAnNTac x 129S4/SvJae
Targeted
Insertion, Intergenic deletion
--
1
--
14

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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