针对Taz的短发夹RNA被定向插入到Rosa26位点。这种shRNA序列由H1/tetO融合驱动的启动子调控。在胚胎干细胞中,确实确认了mRNA的敲除效果。(来源:J:167527)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
插入
--
--
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40

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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