编码外显子被替换成新插入的neo cassette。通过在子宫、睾丸、肾脏、脾脏、肝脏、肺、心脏和大脑的提取物中进行 Western blot 分析,确认了没有蛋白质表达(来源:J:168060)
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The coding exon was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on uterus, testis, kidney, spleen, liver, lung, heart, and brain extracts. (J:168060)