一个包含转录起始点/终止子、内含子间隔序列(IRES)、lacZ基因和新抗性基因的FRT框 cassette被插入到内含子2和3,通过同源重组,整个编码区域被标记为可删除。通过Flp介导的重组,选择性 cassette被移除,使得exon 3被留了下来。(来源:J:166956)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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