在BAC RP23-292B23,包含完整Trpv1基因座的转基因中,通过在第一个外显子的ATG位点插入包含改良cre(icre)和FRT引导的氨苄青霉素抗性基因的磁带,实现了对Trpv1基因的改造。随后,通过Flp表达去除BAC构建中的氨苄青霉素基因。纯化的BAC被注入小鼠卵母细胞的核中。(来源:J:167752)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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