在10号染色体上,插入了新霉素选择座、LoxP位点以及HPRT的5'端序列。这个特定的等位基因仅与Prmt2tm1Yah这一突变体存在于同一条染色体中。构建这个等位基因是为了实现对目标区域Del(10Prmt2-Col6a1)3Yah的敲除(来源:J:167506)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
6
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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