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这些小鼠是通过MICER导向载体创建的。Prmt2靶向使用了从3' HPRT库中选择的载体，而Cstb位点则通过从5' HPRT库中选择的载体进行同源靶向。携带有这种构建的小鼠与Tg(Zp3-cre)93Knw转基因小鼠杂交。Cre表达在雌性小鼠的卵母细胞中，导致10号染色体上一个2.2 MB段的删除，其中包括47个已知基因。(来源：J:167505)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
