转基因包含了小鼠普里昂驱动器和编码野生型人类前体素1的cDNA。通过对转基因动物脑组织提取物进行Northern和Western印迹分析,验证了转基因表达。生成了S8-4、R8-1、H8-4和B8-1线(来源:J:34323)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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插入
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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