The GFAP-rtTA*M2 transgene was designed with the human glial fibrillary acidic protein, GFAP, promoter directing expression of an optimized form of the reverse tetracycline-controlled transactivator (rtTA*M2) protein, followed by a simian virus 40 (SV40) polyadenylation (polyA) signal. Line 1 was generated. (J:166361)