一段编码带有HA标签的TEL-JAK2蛋白的cDNA,来源于急性淋巴细胞白血病病例中融合基因,被插入到Emu/SRalpha启动子/增强子构建的下游。Emu/SRalpha增强子/启动子能确保在淋巴细胞中高效特异表达,但在非淋巴细胞组织中的表达量仅为低到无法检测的水平。(来源:J:166206)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x DBA/2
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插入
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2
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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