1号外显子的编码区域被替换成了人源的HBEGF(链霉素受体)连接到EGFP,并带有floxed neo cassette。通过Cre介导的重组,neo cassette被去除了。这个突变体允许在使用链霉素后,通过条件性的方式消除表达CXCL12的细胞。(来源:J:164657)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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