设计了一个靶向载体,用于在RNA结合蛋白 fox-1同源物2(Rbfox2)基因的6-7号外显子周围插入loxP序列,随后是FRT标记的诺卡因抗性(neo)基因。通过Flp介导的重组,移除了neo基因,使得6号和7号外显子成为可靶向的。(来源:J:165699)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
--
1
--
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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