设计了一个靶向载体,用于在RNA结合蛋白fox-1同源物1(Rbfox1)基因的11-12号外显子周围插入loxP序列,随后是含FRT标记的诺卡因抗性(neo)基因座。通过Flp介导的重组,移除了neo基因座,使得11和12号外显子被标记为可删除。(来源:J:165698)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
--
1
2
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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