在小鼠BAC RP23-116F7的Pdgfra启动子3'位置,插入了cre重组酶基因、SV40晚期polyA位点和一个由-FRT标记的kanamycin抗性基因元件。kanamycin抗性基因元件随后从载体中剔除,经线性化的BAC转染到C57BL/6的囊胚中。该品系由提供遗传背景的实验室通过C57BL/6背景进行维持。(来源:J:165545)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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