从Klf1基因上游50bp包含HS1增强子(EHS1)的序列被移除了。通过E14.5时期肝脏提取物的 Western blot 分析,确实证实了没有蛋白质表达(来源:J:164803)。
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A 50 bp sequence containing the HS1 enhancer (EHS1) upstream of Klf1 was removed. The absence of protein expression was confirmed by western blot analysis on E14.5 liver extracts. (J:164803)