MMTV-lpa1转基因构建包含了1.54kb的MMTVLTR和一段全长的人类LPA1受体,带有FLAG标签,连接到来源于兔子β-球蛋白的KCR片段,该片段包含II号外显子(E2)、II号内含子(I2)、III号外显子(E3)以及polyadenylation信号(rbGpA)。三位MMTV-lpa1的转基因品系(#LPA1-2, #LPA1-7, 和 #LPA1-27)已经通过了遗传学传递至下一代。(来源:J:149661)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
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