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中文
ES细胞在与B82mtA11供体细胞（来源于C3H/An小鼠的L929纤维细胞系）融合前，先用罗丹明6G预处理，目的是去除内源性线粒体和mtDNA。这种供体细胞带有13,997位点的G到A突变（g.13997G>A），导致Proline 25被Leucine替换（p.P25L）。参考文献：J:164405, J:164565
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
