B1-EGFP转基因是通过从人类V-ATPase B1亚基(ATP6V1B1)基因的5'上游区域获取约7kb序列设计的,该序列延伸到但不包含内源性起始密码子,后面跟着增强绿色荧光蛋白(EGFP)编码区域,再接上SV40的早诱导区域polyadenylation信号。构建了线路1和3。(来源:J:162989)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count