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中文
在第2外显子被替换为一个修改过的第2外显子，其中由CTT替换为AAT的密码子7位和CTC替换为AAC的密码子17位，导致在SRP结合位点和内质网膜锚定/移位序列的氨基酸由赖氨酸(Leu)变为天冬酰胺(Asp)，即第7位的L7N和第17位的L17N。插入在修改外显子上游的floxed neo cassette通过Cre介导的重组已被去除。该产物预计会进行线粒体蛋白酶体靶向。(来源：J:163973)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
