目标基因的第二个外显子被1号内含子的LoxP位点和一个FRT-介导的PGK-Neo序列,随后是另一个LoxP位点的2号内含子 flank by 这些元件。通过Flp介导的重组,选择性载体被移除,使得外显子2得以敲除。(来源:J:163812)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv and C57BL/6
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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