通过Cre介导的重组,去除了neo cassette、exon 49和修改过的exon 50。心脏和肝脏的异种个体 Western Blot 分析确认了蛋白表达量的降低。(来源:J:162945)
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Cre mediated recombination removed the neo cassette, exon 49, and the modified exon 50. Reduced protein expression was confirmed by western blot analysis on heart and liver extracts from heterozygotes. (J:162945)