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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(TRP53*R72P)7Dgj
Alias:
p53P #7
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基础信息
表型特征
文献报道
转基因中包含了一个人类的BAC 66H22,其中TRP53基因被修改,使其在第72位编码的是脯氨酸而不是arginine。这两种氨基酸在人类中都是已观察到的多态变异型。第7行构建完成。(来源:J:162466)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
4819620
FVB
--
Insertion, Single point
--
1
--
3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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