Log In|Sign Up
中文
使用一个1.8kb的rat osteocalcin启动子片段，将人类TGF-beta2的cDNA定向表达于成骨细胞中。TGF-beta2的cDNA经过两点突变改造，将编码的正常 cysteines 转换为 serines（位于226和228位点）。共产生了8个杂交瘤系，但仅对D4和D5这两条进行了详细描述。D4杂交瘤系无法培育出纯合子。（来源：J:105791）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
