一个假基因通过同源重组替换掉了3号和4号外显子,可能还涉及5号的部分区域。敲除通过检测肝脏匀浆的 Western blotting 验证了。(来源:J:162148)
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A neo gene replaced exons 3 and 4 and possibly part of 5 by homologous recombination. The knock-out was confirmed by western blotting of liver lysates. (J:162148)