在BAC RP23-163J20的内含子1位置插入了一个floxed neo耐药基因座。E2F结合位点1,TTTCgcgC,被修改为TTTCaaaC。随后,这个BAC通过同源重组导入。随后,通过Cre介导的重组移除了选择性基因座。(来源:J:161509)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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