将一个3.36千碱基的片段,包含cre重组酶、内源性核糖体进入信号(IRES)和FRT-neo-FRT座,插入Hoxb8基因的2号外显子3'端UTR。随后通过与FLPe敲除动物杂交,删除了neo抗性基因座。(来源:J:162102)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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