这个等位基因是通过将Ppibtm1Rjb与携带MMTV-Cre转基因的老鼠杂交产生的,通过靶向的loxP位点删除了第三个外显子。在胸腺细胞中通过 Western blot 实验证实了基因产物的完全丢失,这是一项无功能的等位基因。(来源:J:161748)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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