通过与表达Cre重组酶的 mice杂交,Add3tm1.1Llp基因中的floxed exon 2被去除了。 Western blotting结果显示脾脏中没有检测到该蛋白(来源:J:161920)
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The floxed exon 2 was excised from Add3tm1.1Llp by mating with mice expressing cre recombinase. Western blotting confirmed the absence of the protein in the spleen. (J:161920)