通过Cre介导的染色体片段重排,特别是在Abcg1和Rrp1b附近的LoxP位点之间,会导致大约1.1Mb区域基因的复制,包括Abcg1和Rrp1b,这个区域与人类21q22.3的近端部分存在同源性。(来源:J:161325)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
重复
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--
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16

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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