这个转基因包含了鸡β-actin启动子,后面跟着一个由loxP序列标记的停止子,一个K63W突变的非活性Map3k7激酶,以及一个polyadenylation信号。通过Cre介导的重组,移除了停止子,从而允许非活性Map3k7基因的表达。Map3k7的表达大约增加了4倍,这是表达量最高的品系。(来源:J:117108)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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