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中文
这个转基因载体包含了tet操作子(tetO)和一个CMV的最小启动子，驱动编码一个带有FLAG标签的、来自大鼠α型cAMP响应元件结合蛋白1(CREB1)的突变体的cDNA表达。突变的CREB1在133位的调控丝氨酸被替换为 alanine，从而移除了磷酸化位点。未磷酸化的CREB无法与cAMP响应元件(CREs)结合，阻止野生型CRE和其它CRE结合蛋白的访问。(来源：J:128618)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
