在第15个内含子中插入了floxed neo cassette,通过在肝脏、肾脏、大脑、肺部和嗅觉粘膜组织的 Western blot 分析,证实了蛋白质表达的降低。(来源:J:159168)
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A floxed neo cassette was inserted into intron 15. The reduction in protein expression was confirmed by western blot analysis on liver, kidney, brain, lung, and olfactory mucosa extracts. (J:159168)