在第3外显子上游插入了loxP位点,而在第8外显子下游插入了一个由frt标签和一个5'的loxP位点的neo cassette。通过Flp酶介导的重组,neo cassette被移除,使得3号到8号外显子都被留下了loxP标记。(来源:J:160503)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count