P25TCR转基因小鼠体内携带了一种由H-2Kb启动子调控,能识别Mycobacterium tuberculosis抗原85B中240-254位肽(aa 240-254)结合到I-Ab上的T细胞受体(TCR)。具体来说,构建了两个转基因,一个是包含Valpha5基因片段,另一个是Vbeta11基因,后面跟着polyA序列。小鼠品系P25由此诞生。(来源:J:94023)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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24

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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