在编码区的首尾都插入了LoxP位点。下游3'的LoxP位点后,包含了一个Frt-介导和Cre介导的Frt-flanked pgk-neo cassette。通过这两种重组,Frt和Cre会去除pgk-neo元件,从而删除整个转录单元。(来源:J:159210)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count