Lox511位点被插入到了exon 1C和exon 1B之间的内含子中,以及在frt标签的氨苄西林抗性基因下游的第二个内含子中。随后,通过与表达Flp重组酶的转基因小鼠杂交,这些氨苄西林抗性选择标记被小鼠中剔除了。(来源:J:159972)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
16
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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