这个转基因表达的是丹麦ITM2B等位基因,其中包含ITM2B基因的10个核苷酸重复(795-796位置插入TTTAATTTGT),由叙利亚仓鼠Prnp启动子驱动。建立了两条转基因品系,其中第6号品系表现出较低的转录水平。(来源:J:159279)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
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插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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