Tap2^m1Btlr

The mutation comprises the insertion of a single cytosine nucleotide (C) within a stretch of Cs located between nucleotides 1083 and 1087 of the mRNA sequence (Genbank accession NM_011530), in the fifth of the gene's 12 exons; the number of Cs in the sequence is increased from five to six. The resulting frameshifted transcript is predicted to encode aberrant amino acids from position 312 to 361 and to terminate prematurely at position 362. (J:159355)