将编码Cre重组酶和核定位信号(NLS)的cDNA插入人类3.7kb的SFTPC启动子序列下游,构建了转染基因载体。转基因供体与Z/EG报告小鼠杂交来验证Cre的活性。其中一条转基因系进行了深入研究,被标记为#(原文未提供线号)。(来源:J:158566)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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