在第二个外显子的起始密码子后添加了一个N端的FLAG标签,并在5' UTR的内含子1中插入了一个loxP位点。在内含子5中插入了loxP引导的neo。FLAG标记蛋白的表达量较低。Northern blot结果显示存在多种转录本,且成熟转录本显著减少。(来源:J:158394)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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