基因组序列从exon 4的一部分到exon 6的一部分被替换了新插入的neo cassette。通过在IL4刺激的脾脏B细胞提取物中进行 Western blot 分析,证实了蛋白表达的缺失。(来源:158032)
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Genomic sequence spanning part of exon 4 through part of exon 6 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on IL4-stimulated splenic B cell extracts. (J:158032)